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Vitamin B12: Boosts metabolism, improves mood, and combats fatigue

Research shows this small molecule is an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy regulation and fat metabolism

The results supported further investigation of NNMT inhibition as a drug-development concept

It has been shown to significantly reduce visceral adipose tissue (VAT) in multiple randomized trials (NEJM/phase III evidence

This is the gap between promising preclinical research and verifiable, quality-controlled supply and the reason a published Certificate of Analysis per batch matters

Microbiome 8 (1), e19